Novel Biomarkers for Better Health

Protavio is a leading CRO and CDMO with the aim to improve people’s health through the discovery of novel biomarkers and the development of high-quality in-vitro diagnostic assays (IVD). Harnessing the power of multiplex and multi-omics technologies (Luminex^TM and Olink®) we offer bespoke services for biomarker discovery, custom assay development and manufacturing of IVD and research-use only (RUO) assays. Our expertise encompasses various areas of interest including cancer, immunology, serology, cellular signalling, tobacco research and more. Protavio operates under a ISO9001 certified quality management system and complies with GMP and ISO13485 requirements to translate your discovery idea into a commercial IVD product. We are a trusted service provider for several pharmaceutical companies, SMEs and academic institutions with excellent customer satisfaction and retention rates.

Biomarker Discovery Services

Harnessing the power of multiple omics technologies including Luminex^TM and Olink®, Protavio offers unparalleled screening of > 3000 protein biomarkers simultaneously from the same sample using limited volumes. Select from a list of purpose-built panels that can meet your discovery needs and budget requirements and send your samples to our labs for testing. Our automated workflows, standard operating procedures and experience with various sample types (e.g serum, plasma, CSF, urine, culture supernatants. cellular lysates etc) ensures the generation of high-quality data. Use our bioinformatics services to interrogate your screening datasets and identify biomarkers with best clinical performance characteristics (sensitivity, specificity, PPV, NPV etc).

Custom Assay Development

Protavio has an excellent track record of custom assay development services using Luminex^TM technology, regular ELISA and Lateral Flow platforms. Using diverse coupling techniques, we can immobilise many different types of molecules (antibodies, antigens, oligonucleotides, etc) and employ detection schemes (sandwich assay, direct & indirect ELISA, competitive assay etc) that fit your project specifications. Choose our service to make your own assay either for biomarker discovery purposes or for development of a RUO or IVD product following a successful discovery project.

IVD Services

Turn your biomarker into an IVD commercial product using Protavio’s IVD service. We apply a 3-phase pipeline including a) Feasibility Study, b) Development & Optimisation and c) Transfer to Manufacturing, to ensure full traceability of the development process according to IVDR regulations and provide the customer with all necessary product specifications and production batches required for performance validation and technical file support. Our IVD experts are here to offer additional consultation on platform selection, IP search, regulatory submission and KOL support on your path to commercialization.